Basal ganglia calcification and psychosis in Down's syndrome.
نویسنده
چکیده
A case of basal ganglia calcification (diagnosed in vivo) and schizophreniform psychosis occurring in a young adult with Down's syndrome is reported. A stress-vulnerability model is suggested. Because of the relatively high prevalence of basal ganglia calcification to Down's syndrome, this population appears well suited for systematic study of the neuropsychiatric aspects associated with this neurological condition.
منابع مشابه
A man with purple toes.
1 Wisniewski KE, French JH, Rosen JF, Koslowski PB, Tenner M, Wisniewski HM. Basal ganglia calcification (BGC) in Down's syndrome. Another manifestation of premature aging. Ann NYAcad Sci 1982;396:179-89. 2 Jakab I. Basal ganglia calcification and psychosis in mongolism. Eur Neurol 1978;17:300-14. 3 Lowenthal A, De Deyn P. Striopallidodentate calcifications. In: Joseph AB, Young RR, eds. Moveme...
متن کاملBasal ganglia calcification in Down's syndrome.
The basal ganglia from 33 patients (all over one year of age) with Down's syndrome were examined pathologically. Forty-five per cent had calcification. Basal ganglia calcification was localised to a constant area of globus pallidus and became more prominent with increased age. Calcification and amyloid degeneration of the adjacent blood vessels were present. The proximity of abnormal blood vess...
متن کاملگزارش یک مورد بیماری فار (Fahr's Disease) با تابلوی اختلال خلقی دوقطبی
Fahr’s disease is a progressive and idiopathic basal ganglia calcification with normal metabolism of calcium and phosphore with motor and psychiatric sings and symptoms. Dementi, chorea attetosise, psychosis and depression due to Fahr’s disease are frequently reported, but Fahr’s disease with bipolar mood disorder manifestation is very rare and we found only 3 cases in review of literature fr...
متن کامل[Idiopathic bilateral basal ganglia calcification (Fahr's disease) presenting with psychotic depression and criminal violence: a case report with forensic aspect].
Fahr's disease is a rare neuropsychiatric disease characterized by bilateral intracranial calcification, primarily in the basal ganglia. The more general term, Fahr's syndrome, is used for primary and secondary basal ganglia calcification, regardless of the etiology, but the term Fahr's disease is used to describe primary, idiopathic cases. Fahr's disease may present with neurological symptoms,...
متن کاملFahr’s Disease: An Incidental Finding in a Case Presenting with Psychosis
Fahr’s syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial calcification. We present a 24-year-old male with Fahr disease, presenting with psychosis and recurrent seizures of generalized tonic clonic type, but lacking evidence of a metabolic disorder. His neurological examination was normal. MRI Brain of the patient revealed symmetrical large areas and foc...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 60 700 شماره
صفحات -
تاریخ انتشار 1984